Structure
Secondary Structure
Helix
Alpha-helical secondary structure segment.
Strand
Beta-strand segment with chain direction indicated.
Turn
Turn region connecting distinct secondary structure elements.
Tracks
Sequence and Physicochemical Tracks
A
Query Sequence
Residue letter cell for the target sequence at this position.
A
Exact Match
Residue is identical to the query sequence at this position.
S
Similar Substitution
Residue differs from the query but remains a conservative substitution.
Accessibility / Buried
Dark blue indicates very low surface accessibility and mostly buried residues.
Accessibility / Intermediate
Grey-blue indicates partial exposure between buried and exposed states.
Accessibility / Accessible
Light blue indicates residues that are more solvent-accessible.
Accessibility / Highly Exposed
Gold indicates residues with strong surface exposure.
Hydropathy / Hydrophobic
Orange indicates locally hydrophobic regions, often buried or lipid-facing.
Hydropathy / Neutral
Gray indicates locally intermediate physicochemical character.
Hydropathy / Hydrophilic
Blue indicates locally hydrophilic regions with stronger aqueous compatibility.
Confidence Tracks
Very High
pLDDT ≥ 90 indicates very high local confidence.
Confident
70 ≤ pLDDT < 90 indicates a generally reliable region.
Low
50 ≤ pLDDT < 70 indicates limited confidence and should be interpreted carefully.
Very Low
pLDDT < 50 indicates an unstable or weakly predicted region.
Contacts
Contact Strength and Symbols
Strong Protein Contact
Based on the shortest non-hydrogen atom distance: below 3.2 A.
Weak Protein Contact
Based on the shortest non-hydrogen atom distance: between 3.2 A and 3.7 A, inclusive.
Intramolecular Disulfide
Green S marks a CYS-CYS disulfide bond within the same protein chain.
Intermolecular Disulfide
Cyan S marks a CYS-CYS disulfide bond between different protein chains.
Same-position Protein Contact
Contact partners share the same residue number and residue identity.
Ion
Indicates a contact with an ion partner.
Nucleic Acid
Indicates a contact with a nucleic-acid partner.
Porphyrin-like Ligand
Indicates contact with a porphyrin or related macrocyclic ligand.
Glycan
Indicates contact with a carbohydrate ligand.
Other Ligand
Indicates contact with another non-protein, non-nucleic-acid, non-glycan partner.
Multiple Contacts
Indicates multiple contact types at the same residue position.